Here are the following supported upgrade paths and compatibility for the Nvidia Grid Drivers

Release notes containing compatibility can be found by googling the below, substituting Rxyz for your version
Virtual GPU Software Rxyz for VMware vSphere Release Notes, the link is here, you will need to substitute the vGPU version if yours is different

Here is an example table for the supported versions

Here the vGPU Manager is referring to the drivers on the host, like ESXi
And the guest VM drivers are that on your Windows/Linux guest OS
The Guest VM drivers should match the host, the only time they should differ is during an upgrade

450 Series

You can use this version on your host and it will work with the following Guest versions
440/v10
450/v11

460 Series

You can use this version on your host and it will work with the following Guest versions
450/v11
460/v12

470 Series

You can use this version on your host and it will work with the following Guest versions
450/v11
460/v12
470/v13

535 Series

You can use this version on your host and it will work with the following Guest versions
470/v13
525/v15
535/v16

550 Series

You can use this version on your host and it will work with the following Guest versions
550/v17
535/v16

Author

By Leaha